An Israeli Company Wants to Treat Tourette Syndrome With Cannabis
Therapix Biosciences announced the successful completion of phase 2 clinical trial of its cannabinoid-based drug, conducted at Yale University Monday
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Tourette, which is usually diagnosed in early childhood, is a neurological disorder that affects 1 in every 360 children, according to the U.S. Centers for Disease Control and Prevention (CDC). It is characterized by repetitive, involuntary movements and noises called tics. In 10%-15% of those affected the symptoms are severe enough to be considered a disability, according to the U.S. National Institute of Neurological Disorders and Stroke, and the most common medical treatment is antipsychotics, which are not completely effective and can have problematic side effects.
Conducted at Yale University, Therapix Biosciences' 12-week trial enrolled 16 adult participants. The average tic reduction across all 16 participants was 21%, the company said, with six experiencing an improvement of over 25%, and 12 participants electing to continue into a 24-week extension phase.
"We believe that the efficacy demonstrated in this study further reinforce the potential role of cannabinoids in the field of central nervous system and movement disorders, and suggests that Therapix Biosciences may have a proprietary cannabinoid product candidate in the treatment of Tourette syndrome," Chairman and interim CEO of Therapix Biosciences Ascher Shmulewitz said in a statement.